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The UK Pregnancies Better Eating and Activity Trial (UPBEAT) is a randomised controlled trial done at antenatal clinics in eight hospitals in multi-ethnic, inner-city locations in the UK. We recruited pregnant women (15-18 weeks plus 6 days of gestation) older than 16 years who were obese (BMI ≥30 kg/m 2). We randomly assigned participants to either a behavioural intervention or standard~Metformin has no significant effect on birthweight percentile in obese pregnant women. Further follow-up of babies born to mothers in the EMPOWaR study will identify longer-term outcomes of metformin in this population; in the meantime, metformin should not be used to improve pregnancy outcomes in obese women without diabetes./The UPBEAT trial has added to growing evidence showing the ineffectiveness of mixed interventions based on diet and lifestyle on the incidence of gestational diabetes and large babies, particularly in overweight and obese women.*The UPBEAT trial aimed to find out whether, by making changes to the food obese pregnant women eat and increasing physical activity reduces these problems, and leads to improved long term health for mother and child. The UPBEAT trial was funded by the UK National Institute for Health Research (NIHR).^The objective of this study is to investigate the effects of the UK Pregnancies Better Eating and Activity Trial (UPBEAT) behavioral intervention on dietary patterns in obese pregnant women. Dietary patterns were derived from Food Frequency$Methods Study design We conducted a two-arm, parallel-group randomised feasibility trial comparing the OnTrack Rehab intervention plus usual care with usual care alone with an allocation ratio of 1:1. A nested process evaluation and economic evaluation were performed in parallel with the trial./The study found that the UPBEAT intervention, an intense theoretically based intervention in obese pregnant women which combined dietary and PA advice, did not reduce the risk of gestational diabetes mellitus or large-for-gestational age infants, despite successfully reducing the dietary glycaemic load.


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